BDBM50357650 CHEMBL1914742

SMILES CC(C)N1CCN(CC1)c1cnc2ccc(cc2n1)-c1cnc(Cl)c(NS(=O)(=O)c2ccc(F)cc2)c1

InChI Key InChIKey=MVPHPMFJESRQLE-UHFFFAOYSA-N

Data  1 KI  6 IC50

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50357650   

TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform(Homo sapiens (Human))
Amgen

Curated by ChEMBL

LigandBDBM50357650(CHEMBL1914742)Copy SMILESCopy InChI

Affinity DataIC50:  9.60nMAssay Description:Inhibition of N-terminus polyHis-tagged human recombinant PI3Kbeta expressed in baculovirus infected insect Sf9 cells using phosphoinositol-4,5-bisph...More data for this Ligand-Target Pair

Target InfoPDBMMDBNCI pathwayReactome pathwayKEGG
UniProtKB/SwissProt
B.MOADDrugBankantibodypediaGoogleScholar

Ligand InfoCHEMBLPC cidPC sidPatentsSimilars

In DepthDetails ArticlePubMed
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